Dihydroceramide Desaturase-1 (Des1) Inhibitors for the Treatment of Fibrotic Disease

Suppression of Post-Ischemic Cardiac Remodelling and Inflammatory Response by a Novel Sphingolipid Modifier, CIN038

BH Wang, F Savira, X Xiong, DD Donner, H Kiriazis, A Brown, L Huang, N Mellet, K Huynh, PJ Meikle, D Creek, C Reid, BL Flynn, DM Kaye, D Liew, RR Magaye

2026-07-01

In patients with myocardial infarction (MI), the level of sphingolipids, such as ceramide (Cer), is elevated and is associated wit..